Duke Center for Systems Biology
Duke University, Durham, United States
The Duke Center for Systems Biology (DCSB) was established to characterize and understand the dynamics of biological networks, including both the dynamics of network states—changes in concentrations of molecular species as different portions of a network are utilized—and the dynamics of network structures—changes in the components or interactions of a network as genetic mutations accrue through evolution. The DCSB builds upon the close working relationships between computational and experimental scientists across the Schools of Arts & Sciences, Engineering, and Medicine, all nestled together on Duke's expansive neo-Gothic campus. Among other activities, the DCSB funds research projects that advance the Center's mission.
Research Topics Currently Explored at the Duke CSB
- Bayesian statistical methods
- Cell cycle control
- Differentiation and development
- Evolution of networks
- Expression profiling
- High-throughput microscopy
- Logical Functions and Boolean Networks
- Regulatory networks
- Signal transduction
- Synthetic biology
Contact person for international outreach:
. Assistant Professor of Biostatistics and Bioinformatics
Current examples of international collaborations of Duke faculty:
Asia: Projects with the joint Duke/National University of Singapore Medical School, on modeling linked to tropical diseases (statisticis, mathematical modelling of immune response profiles, etc). Additionally, there is a commitment for exchange with the Genome Institute of Singapore.
Europe: Projects with the Max Planck Institute for Molecular Cell Biology and Genetics in Dresden, on the evolution of gene expression and high-throughput imaging of gene expression patterns in to.
Relevant quantitative or systems biology graduate programs:
Computational Biology & Bioinformatics
Funding opportunities:
The DCSB invites proposals for short-term visitors (students, postdocs, or faculty) on a rolling bases. We have a strong preference for collaborative projects that engage members of our group. Visitors will receive reimbursement for travel and housing expenses and an honorarium to cover incidental expenses. Click here for more information.