The Center for Genome Dynamics
The Jackson Laboratory, Bar Harbor, Maine
The Center for Genome Dynamics embraces a systems approach to genetics, with an emphasis on rodent models of complex disease-related phenotypes. We are addressing questions that will lead to an understanding of how whole genome properties and networks of genetic interactions arise through the process of evolution. Center projects are designed to address different aspects and implications of genome organization, recognizing that the genome is a dynamic system over generational, developmental and evolutionary time. We are applying computational approaches to large data sets generated by the Center to describe the interactions between genome organization, gene expression, phenotype determination and the impact of recombination hotspots. The synthesis of all these lines of investigation is required to address the implications of genome dynamics.
Research Topics Currently Explored at the CGD
- Comparative genomics
- Epigenomics
- Evolutionary Genetics
- Expression Profiling
- Metabolomics
- Research in vivo
Contact person for general information:
Imogen Hurley, Research Programs Manager, The Jackson Laboratory.
Ongoing international exchange:
Recent international visitors to the CGD have included:
Ritsert Jansen, Professor of Bioinformatics, Groningen Bioinformatics Centre, University of Groningen
Dates: September 20-30, 2008
Accompanied by: Yang Li, Bruno Tesson
Christian Deschepper, Research Unit Director, Experimental Cardiovascular Biology, Institut de Recherches Cliniques de Montreal
Dates: July 16-19, 2008
Helge Goessling, Diploma Student, Humboldt University, Berlin
Dates: June 7-26, 2008
Gudrun Brockmann, Professor, Department of Animal Sciences, Humboldt University, Berlin
Dates: March-September 2007
Funding opportunities:
[pending information]